Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or increases the chance by Items are an integral part of gameplay in The Binding of Isaac series. This page was last edited on 23 Januaryat Game content and materials are trademarks and copyrights of their respective publisher and its licensors. Navigation menu Namespaces Page Discussion. Polyphemus is an example of an item that provides a very high Damage stat. These multipliers do not stack for example, picking up both Cricket's Head and Magic Mushroom will result in an overall 1. Most damage multipliers stack for example, Proptosis and Eve's Mascara both provide a 2x multiplier picking up both will give a total multiplier of 4x. This means that if a character starts with 3. Damage multipliers do not simply multiply the character's damage once the damage stat is constantly recalculated and the damage multipliers are multiplied with the end result. Some items multiply damage rather than simply adding to it. This does not apply to other characters, however. The character base damage of each tear is calculated multiplying the base damage of 3. Flat damage modifiers and special adjustments like Polyphemus or Sacred Heart happen after the main formula. The higher a character's base damage, the more effective Damage Ups will be for that character. This formula makes most damage upgrades less potent the more that Isaac has.Īnother Pentagram increases this to 6. Tears will grow and shrink when your damage changes, but tears of a certain size do not have a specific damage value, and two tears of the same size in two different runs are likely to have different damage values. However, tear size is not always a valid indication of how much damage your tears will do. As damage increases, the size of the tears increases as well. Cards and Runes.Damage refers to the amount of damage each tear deals to enemiesand is represented by a sword. This page was last edited on 9 Februaryat Game content and materials are trademarks and copyrights of their respective publisher and its licensors.Īll rights reserved. Hidden categories: Pages using duplicate arguments in template calls Deprecated.
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The Virus Inflicts poison to enemies who make contact with Isaac. Synthoil Increases damage by 1, range by 5. Growth Hormones Increases damage by 1 and speed by 0. If a needle kills an enemy, it bursts into more needles.Įxperimental Treatment Randomly increases and decreases some of the character's stats. Euthanasia Adds a chance to fire needles.
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Syringes Adrenaline Increases damage based on how many empty heart containers Isaac has.